HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 22503413, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-(5-bromo-2-pyridinyl)butanamide | HCID 876084 | — |
| Reactant | 1-(1-Ethylpiperazin-4-yl)-3-bromoisoquinoline | HCID 22502447 | — |
| Product | HCID 22503413 | HCID 22503413 | — |
Reaction Steps
In the same manners sequentially as in Examples 161-2 and 20, the free compound of the title compound (338 mg, yield; 40%) from 5-bromo-2-propylcarbonylaminopyridine (3.11 g) and 3-bromo-1-(4-ethylpiperazin-1-yl)isoquinoline (514 mg). The resulting free compound was converted into a hydrochloride in a conventional manner, to give the hydrochloride of the title compound as yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06875761B2 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-7670bd348061409aa9496db3dd70637e |
| Source note | uspto-grants-2005_04 |