Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1814695생성일: 2026년 10월 25일
Pyridine → 3-{3-(4-tert-butylphenyl)-3-[4-(2H-tetrazol-5-ylcarbamoyl)benzyl]ureido}benzoic acid pentafluorophenyl ester
https://huagongshe.com/reaction/1814695
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | Pentafluorophenyl Trifluoroacetate | HCID 4327891 | — |
| 반응물 | 3-{3-(4-tert-Butylphenyl)-3-[4-(2H-tetrazol-5-ylcarbamoyl)benzyl]ureido}benzoic acid | HCID 22501965 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3-{3-(4-tert-butylphenyl)-3-[4-(2H-tetrazol-5-ylcarbamoyl)benzyl]ureido}benzoic acid pentafluorophenyl ester | HCID 18346946 | — |
반응 단계
To the above resin bound 3-{3-(4-tert-butylphenyl)-3-[4-(2H-tetrazol-5-ylcarbamoyl)benzyl]ureido}benzoic acid was added a solution of pyridine (500 μL) in DMF (5 mL) followed by pentafluorophenyl trifluoroacetate (850 μL). The mixture was shaken for 4 hours at 25° C., filtered and washed with DMF (2×10 mL), affording the resin bound title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US06875760B2 |
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| 출처 데이터셋 | uspto-grants-2005_04 |
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| ORD ID | ord-037a32ba1b414c8898caadacac476373 |
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| 출처 메모 | uspto-grants-2005_04 |
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