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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1814950Generated: October 31, 2026

Methylamine → 6-AMINO-1-BENZYL-5-METHYLAMINOURACIL

https://huagongshe.com/reaction/1814950

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant6-AMINO-1-BENZYL-5-BROMOURACILHCID 822149—
Product6-AMINO-1-BENZYL-5-METHYLAMINOURACILHCID 726225—

Reaction Conditions

Temperature5 °C

Reaction Steps

6-Amino-1-benzyl-5-bromouracil (134 g) was stirred with 40% aqueous methylamine solution (750 ml) for 24 hours. After cooling to 5° C., the precipitate was filtered and dried under suction to provide 6-amino-1-benzyl-5-methylaminouracil (55 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06878715B1
Source datasetuspto-grants-2005_04
ORD IDord-03cb572469a64cfe963762ddab5d3eb1
Source noteuspto-grants-2005_04