Hydrochloric Acid → HCID 54015081, compound

Participants

Reaction Steps

To a solution of (S)-1-(5-acetoxyhexyl)-7-benzyl-8-chloromethyl-3-methylxanthine (8.7 g, 19.5 mmol) was added a solution of hydrogen chloride in ether (1.0 M, 20 ml). After stirring at room temperature for 24 hours, the solvent was evaporated under reduced pressure to give (S)-1-(5-hydroxyhexyl)-7-benzyl-8-chloromethyl-3-methylxanthine (7.0 g, 89% yield) as a white solid.

Provenance & Evidence