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HRID1815065

反应详情

EQUATION

反应方程式

HRID 1815065 反应方程式

REACTANTS

反应物

3
6-Chloro-2-picoline 分子结构式
HCID87601

6-Chloro-2-picoline

C6H6ClN

n-boc-4-hydroxypiperidine 分子结构式
HCID643502

n-boc-4-hydroxypiperidine

C10H19NO3

tert-Butyl 4-[(pyridin-2-yl)oxy]piperidine-1-carboxylate 分子结构式
HCID21906039

tert-Butyl 4-[(pyridin-2-yl)oxy]piperidine-1-carboxylate

C15H22N2O3

PRODUCTS

产物

1
HCID 21906072 分子结构式
HCID21906072

未命名化合物

PROCEDURE

实验过程

Prepared from 1-Boc-4-hydroxypiperidine and 2-chloro-6-methylpyridine using methods substantially equivalent to those described for the synthesis of 1-Boc-4-(pyridin-2-yloxy)piperidine. The product was purified by chromatography over silica gel, eluting with a gradient of 0-15% ethyl acetate in hexanes.

WORKUP

后处理

  1. customThe product was purified by chromatography over silica gel
  2. washeluting with a gradient of 0-15% ethyl acetate in hexanes