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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1815065Generated: October 31, 2026

6-Chloro-2-picoline → HCID 21906072, compound

https://huagongshe.com/reaction/1815065

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-2-picolineHCID 87601—
ReactantTert-butyl 4-hydroxypiperidine-1-carboxylateHCID 643502—
Reactant1-Boc-4-(2-pyridyloxy)piperidineHCID 21906039—
ProductHCID 21906072HCID 21906072—

Reaction Steps

Prepared from 1-Boc-4-hydroxypiperidine and 2-chloro-6-methylpyridine using methods substantially equivalent to those described for the synthesis of 1-Boc-4-(pyridin-2-yloxy)piperidine. The product was purified by chromatography over silica gel, eluting with a gradient of 0-15% ethyl acetate in hexanes.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06878725B2
Source datasetuspto-grants-2005_04
ORD IDord-7435b393ed2c437c9c653d95a8ffe1e8
Source noteuspto-grants-2005_04