1-Butanol → 4-[4-(3-Piperidin-1-yl-propoxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17]([O:20][CH2:21][CH2:22][CH2:23][Cl:24])[cH:18][cH:19]2)[CH2:12][CH2:13]1.[CH2:25]1[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]1.[CH2:39]([OH:40])[CH2:41][CH2:42][CH3:43].[I-:38].[K+:37].[Na+:31].[Na+:32].[O-:33][C:34](=[O:35])[O-:36]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17]([O:20][CH2:21][CH2:22][CH2:23][N:28]3[CH2:27][CH2:26][CH2:25][CH2:30][CH2:29]3)[cH:18][cH:19]2)[CH2:12][CH2:13]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-3b8104bc52a5444fbf4885f9050d7d33
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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