Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Hexahydro-1,4-diazepine | HCID 68163 | — |
| Reactant | HCID 86592292 | HCID 86592292 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86594149 | HCID 86594149 | — |
Reaction Steps
5 g of homopiperazine (0.05 mol) and 6 ml of dry DMF are charged to a fully equipped round-bottomed flask. The mixture is brought to 100° C. 1.65 g of 2-(4-methoxyphenylazo)-1,3-dimethyl-3H-imidazol-1-ium perchlorate are added over 20 min. The reaction mixture is maintained for 1 hour at 100° C. with stirring and then it is allowed to cool. The reaction mixture is then poured, with stirring, into 150 ml of ethyl acetate. A precipitate forms and it is separated from a gum. This precipitate is recovered by filtration and it is washed 3 times with ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06881230B2 |
|---|
| Source dataset | uspto-grants-2005_04 |
|---|
| ORD ID | ord-72cd2578f14f4a78a861010178c1d20c |
|---|
| Source note | uspto-grants-2005_04 |
|---|
