5-Chloro-2-nitrobenzoic acid → 5-Chloro-2-nitrobenzoyl chloride

HRID 1815740Notes

Reaction equation

HRID 1815740 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:11]([O-:13])=[O:12])=[C:6]([CH:10]=1)[C:7](O)=[O:8].S(Cl)([Cl:16])=O>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:11]([O-:13])=[O:12])=[C:6]([CH:10]=1)[C:7]([Cl:16])=[O:8]

Participants

3

Reactant 2

HCID 172865-Chloro-2-nitrobenzoic acidHCID 24386Thionyl Chloride

Product 1

HCID 27236855-Chloro-2-nitrobenzoyl chlorideYield 98%

Procedure

100.00 g (0.50 mol) of 5-chloro-2-nitrobenzoic acid were mixed with 72.20 g (0.61 mol) of thionyl chloride and the mixture was heated under reflux for 2 h. The excess thionyl chloride was removed in vacuo. 106.50 g (ca. 98%) of crude 5-chloro-2-nitro-benzoyl chloride were obtained as an oil.

Workup

  1. temperaturethe mixture was heated
  2. temperatureunder reflux for 2 h
  3. customThe excess thionyl chloride was removed in vacuo

Sources & evidence

ORD record
ord-8e24ab24ddcd484ab70239a7988699b9
Source dataset
uspto-grants-2005_04
Patent number
US06881735B2

Reaction notes

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