Hydrochloric Acid → HCID 69744790, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 0.48 gm (2.1 mMol) cis-3-methyl-4-(5-fluorobenzofur-7-yl)piperidine in 5 mL ethyl acetate was treated with 5.0 mL 1N hydrogen chloride in diethyl ether. The resulting slurry was stirred for 1.5 hours at 0° C. and was then filtered under reduced pressure. The solid was washed with diethyl ether and dried under reduced pressure to provide 0.50 gm (89%) of the title compound.

Provenance & Evidence