反应详情

Beginning with 0.84 gm (2.2 mMol) 1-benzyl-3-methyl-4-hydroxy-4-(4-trifluoromethylbenzofur-7-yl)piperidine and 1.6 gm p-toluenesulfonic acid monohydrate, 0.18 gm of the desired compound were prepared essentially as described in EXAMPLE 3.