Hydrochloric Acid → HCID 69746335, compound

HRID 1815853Notes

Reaction equation

HRID 1815853 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][C@H:11]([C:14]2[C:22]3[O:21][CH:20]=[CH:19][C:18]=3[C:17]([F:23])=[C:16]([F:24])[CH:15]=2)[C@H:10]([CH3:25])[CH2:9]1)=O)(C)(C)C.[ClH:26]>O1CCOCC1>[ClH:26].[CH3:25][C@H:10]1[C@@H:11]([C:14]2[C:22]3[O:21][CH:20]=[CH:19][C:18]=3[C:17]([F:23])=[C:16]([F:24])[CH:15]=2)[CH2:12][CH2:13][NH:8][CH2:9]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 69744433HCID 69744433, compound

Product 1

HCID 69746335HCID 69746335, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

The title compound was prepared by treating cis-1-(tert-butoxycarbonyl)-3-methyl-4-(4,5-difluorobenzofur-7-yl)piperidine with 4N hydrochloric acid in dioxane essentially as described in EXAMPLE 10.

Sources & evidence

ORD record
ord-143dfa2ae7b14415a593d35876e7fd37
Source dataset
uspto-grants-2005_04
Patent number
US06881733B1

Reaction notes

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