HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tributylstannane → HCID 69746630, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tributylstannane | HCID 5948 | — |
| Reactant | HCID 22495634 | HCID 22495634 | — |
| Reactant | HCID 22495734 | HCID 22495734 | — |
| Product | HCID 69746630 | HCID 69746630 | 77% |
Reaction Steps
Beginning with 1.24 gm (3.48 mMol) 1-benzyl-3-methyl-4-hydroxy-4-(4,6-difluorobenzofur-7-yl)piperidine, 1-benzyl-3-methyl-4-(methyl oxoacetoxy)-4-(4,6-difluorobenzofur-7-yl)piperidine were prepared essentially as described in EXAMPLE 16. This material was treated with tri(n-butyl)tin hydride essentially as described in EXAMPLE 16 to prepare 0.91 gm (77%) of the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06881733B1 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-5975aad1dab54d90a3a4712510c852cb |
| Source note | uspto-grants-2005_04 |