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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1815873Generated: October 26, 2026

1-Benzyl-3,3-dimethylpiperidin-4-one → 3,3-Dimethyl-4-(5-chlorobenzofur-7-yl)-1,2,3,6-tetrahydropyridine hydrochloride

https://huagongshe.com/reaction/1815873

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Benzyl-3,3-dimethylpiperidin-4-oneHCID 9794413—
Reactant7-Bromo-5-chloro-1-benzofuranHCID 22144720—
Product3,3-Dimethyl-4-(5-chlorobenzofur-7-yl)-1,2,3,6-tetrahydropyridine hydrochlorideHCID 22495640—

Reaction Steps

Beginning with 5-chloro-7-bromobenzofuran and 1-benzyl-3,3-dimethyl-4-oxopiperidine, 0.29 gm of the title compound were prepared essentially as described in EXAMPLE 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06881733B1
Source datasetuspto-grants-2005_04
ORD IDord-d09794c6975249e4a887ed19f490ab8c
Source noteuspto-grants-2005_04