HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 59344913, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-bromo-1-(3-fluoro-benzyl)-1H-indole-2-carboxylic acid benzyl ester | HCID 59344917 | — |
| Product | HCID 59344913 | HCID 59344913 | — |
Reaction Steps
4-Bromo-1-(3-fluoro-benzyl)-1H-indole-2-carboxylic acid amide was prepared from 4-bromo-1-(3-fluoro-benzyl)-1H-indole-2-carboxylic acid benzyl ester by hydrolysis with ethanolic NaOH, followed by treatment with oxalyl chloride and then ammonia, as described in steps 3 and 4 of Example 1 MS: 348 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07741326B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-b9888c749ea74620b01ea18cf42b50e9 |
| Source note | uspto-grants-2010_06 |