反应详情

4-Bromo-1-(3-fluoro-benzyl)-1H-indole-2-carboxylic acid amide was prepared from 4-bromo-1-(3-fluoro-benzyl)-1H-indole-2-carboxylic acid benzyl ester by hydrolysis with ethanolic NaOH, followed by treatment with oxalyl chloride and then ammonia, as described in steps 3 and 4 of Example 1 MS: 348 (M+H)+.