Propylamine → HCID 9795167, compound

HRID 1816247Notes

Reaction equation

HRID 1816247 reaction equation
[NH2:1][C:2]1[CH:13]=[CH:12][CH:11]=[CH:10][C:3]=1[C:4]([NH:6][CH2:7][CH2:8][CH3:9])=[O:5].[CH2:14]([NH2:17])[CH2:15]C.[C:18]12[C:24](=CC=CC=1)[NH:23]C(=O)OC2=O>>[NH:17]1[CH2:14][CH2:15][N:23]=[C:24]1[CH2:18][NH:1][C:2]1[CH:13]=[CH:12][CH:11]=[CH:10][C:3]=1[C:4]([NH:6][CH2:7][CH2:8][CH3:9])=[O:5]

Participants

4

Reactant 3

HCID 7852PropylamineHCID 8359Isatoic AnhydrideHCID 16533352-amino-N-propylbenzamide

Product 1

HCID 9795167HCID 9795167, compound

Procedure

2-Amino-N-propylbenzamide (prepared from propylamine and isatoic anhydride, using, the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give 2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-N-propylbenzamide, isolated as the hydrochloride salt.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-cf68c5bdc7bf4f56969d3e756f1f53c9
Source dataset
uspto-grants-2005_04
Patent number
US06884801B1

Reaction notes

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