Allylamine → HCID 22493227, compound

HRID 1816248Notes

Reaction equation

HRID 1816248 reaction equation
[CH2:1]([NH:4][C:5](=[O:13])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[NH2:12])[CH:2]=[CH2:3].[CH2:14]([NH2:17])[CH:15]=C.[C:18]12[C:24](=CC=CC=1)[NH:23]C(=O)OC2=O>>[CH2:1]([NH:4][C:5](=[O:13])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[NH:12][CH2:15][C:14]1[NH:17][CH2:18][CH2:24][N:23]=1)[CH:2]=[CH2:3]

Participants

4

Reactant 3

HCID 7853AllylamineHCID 8359Isatoic AnhydrideHCID 2062656N-allyl-2-aminobenzamide

Product 1

HCID 22493227HCID 22493227, compound

Procedure

N-Allyl-2-amino benzamide (prepared from allylamine and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give N-allyl-2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]benzamide, isolated as the hydrochloride salt.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-23dbf787be854ceebb1efbf99ca9b9cf
Source dataset
uspto-grants-2005_04
Patent number
US06884801B1

Reaction notes

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