Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816262Generated: October 31, 2026

Butylamine → HCID 22493277, compound

https://huagongshe.com/reaction/1816262

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButylamineHCID 8007—
Reactant5-Fluoroisatoic anhydrideHCID 288560—
ReactantHCID 22493368HCID 22493368—
ProductHCID 22493277HCID 22493277—

Reaction Steps

2-Amino-N-butyl-5-fluorobenzamide (prepared from butylamine and 6-fluoro-2H-3,1-benzoxazine-2,4(1H)-dione using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give N-butyl-2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-5-fluorobenzamide, isolated as the hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884801B1
Source datasetuspto-grants-2005_04
ORD IDord-bbed3f4cec5c48428c45841328606d76
Source noteuspto-grants-2005_04