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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816263Generated: October 30, 2026

Cyclopropylamine → HCID 22493363, compound

https://huagongshe.com/reaction/1816263

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropylamineHCID 69828—
Reactant5-Fluoroisatoic anhydrideHCID 288560—
ReactantHCID 22493342HCID 22493342—
ProductHCID 22493363HCID 22493363—

Reaction Steps

2-Amino-N-cyclopropyl-5-fluorobenzamide (prepared from cyclopropylamine and 6-fluoro-2H-3,1-benzoxazine-2,4(1H)-dione using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give N-cyclopropyl-2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-5-fluorobenzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884801B1
Source datasetuspto-grants-2005_04
ORD IDord-d3d49a7eed54407badfd42516d06d064
Source noteuspto-grants-2005_04