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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816264Generated: October 31, 2026

Cyclopropylamine → HCID 22493311, compound

https://huagongshe.com/reaction/1816264

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropylamineHCID 69828—
Reactant5-methyl-2,4-dihydro-1H-3,1-benzoxazine-2,4-dioneHCID 10487522—
ReactantHCID 16795175HCID 16795175—
ProductHCID 22493311HCID 22493311—

Reaction Steps

2-Amino-N-cyclopropyl-6-methylbenzamide (prepared from cyclopropylamine and 5-methyl-2H-3,1-benzoxazine-2,4(1H)-dione using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give N-cyclopropyl-2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-6-methylbenzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884801B1
Source datasetuspto-grants-2005_04
ORD IDord-738d21dabbdf45b38832a0d19cf8ebd1
Source noteuspto-grants-2005_04