Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816265Generated: October 31, 2026

Pyrrolidine → HCID 22493385, compound

https://huagongshe.com/reaction/1816265

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant6-Fluoroisatoic anhydrideHCID 2783057—
ReactantHCID 22493346HCID 22493346—
ProductHCID 22493385HCID 22493385—

Reaction Steps

{2-Amino-6-fluorophenyl}(1-pyrrolidinyl)methanone (prepared from pyrrolidine and 5-fluoro-2H-3,1-benzoxazine-2,4(1H)-dione using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give {2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-6-fluorophenyl}(1-pyrrolidinyl)methanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884801B1
Source datasetuspto-grants-2005_04
ORD IDord-4ec5b4cea9bd4706b11fe586decacb1c
Source noteuspto-grants-2005_04