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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816266Generated: November 2, 2026

Pyrrolidine → HCID 22493345, compound

https://huagongshe.com/reaction/1816266

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant4-Chloroisatoic anhydrideHCID 329105—
ReactantHCID 16776289HCID 16776289—
ProductHCID 22493345HCID 22493345—

Reaction Steps

(2-Amino-4-chlorophenyl)(1-pyrrolidinyl)methanone (prepared from pyrrolidine and 7-chloro-2H-3,1-benzoxazine-2,4(1H)-dione using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give (4-chloro-2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]phenyl}(1-pyrrolidinyl)methanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884801B1
Source datasetuspto-grants-2005_04
ORD IDord-bf3e16a4f7a443f3961f9d9489970745
Source noteuspto-grants-2005_04