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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816276Generated: November 1, 2026

Aniline → HCID 54077451, compound

https://huagongshe.com/reaction/1816276

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
Reactant1-Fluoro-2-nitrobenzeneHCID 73895—
ReactantN-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2-(1-pyrrolidinyl)anilineHCID 22493417—
ProductHCID 54077451HCID 54077451—

Reaction Steps

Under conditions similar to those used for the preparation of N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2-(1-pyrrolidinyl)aniline (Example 64), hexamethyleneimine was reacted with 2-fluoronitrobenzene, the nitro group was reduced and the aniline was coupled with CMI to give 2-(1-azepinyl)-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline .

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884801B1
Source datasetuspto-grants-2005_04
ORD IDord-a862daa34cad486d98f886c27c4f7372
Source noteuspto-grants-2005_04