Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816304Generated: November 2, 2026

Pyrrolidine → HCID 22493321, compound

https://huagongshe.com/reaction/1816304

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant5-Bromoisatoic AnhydrideHCID 288561—
ReactantHCID 22493358HCID 22493358—
ProductHCID 22493321HCID 22493321—

Reaction Steps

{2-amino-5-bromophenyl}(1-pyrrolidinyl)methanone (prepared from pyrrolidine and 6-bromo-2H-3,1-benzoxazine-2,4(1H)-dione using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give {5-bromo-2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]phenyl}(1-pyrrolidinyl)methanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884801B1
Source datasetuspto-grants-2005_04
ORD IDord-f16db3862e974e2f8f1bd1a88b88d810
Source noteuspto-grants-2005_04