Pyrrolidine → HCID 22493220, compound

Participants

Reaction Steps

{2-Amino-5-bromo-3-methylphenyl}(1-pyrrolidinyl)methanone (prepared from pyrrolidine and 6-bromo-8-methyl-2H-3,1-benzoxazine-2,4-(1H)-dione using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give {5-bromo-2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-3-methylphenyl}(1-pyrrolidinyl)methanone.

Provenance & Evidence