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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816568Generated: November 1, 2026

2-Methoxy-4-(trifluoromethyl)benzoic acid → 2-[4-Methoxy-3-({[2-methoxy-4-(trifluoromethyl)benzoyl]amino}methyl)benzyl]butanoic acid

https://huagongshe.com/reaction/1816568

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methoxy-4-(trifluoromethyl)benzoic acidHCID 3690873—
ReactantEthyl 2-[3-(aminomethyl)-4-methoxybenzyl]butanoateHCID 11108255—
Product2-[4-Methoxy-3-({[2-methoxy-4-(trifluoromethyl)benzoyl]amino}methyl)benzyl]butanoic acidHCID 2249437262.6%

Reaction Steps

0.24 g of 2-methoxy-4-(trifluoromethyl)benzoic acid and 0.3 g of ethyl 2-[3-(aminomethyl)-4-methoxybenzyl]butanoate were treated in the same manners as in Example 19d) and then in Example 19e), to give 0.3 g of 2-[4-methoxy-3-({[2-methoxy-4-(trifluoromethyl)benzoyl]amino}methyl)benzyl]butanoic acid as a pale yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884821B1
Source datasetuspto-grants-2005_04
ORD IDord-365367140c5b4218bdf616ff58d19063
Source noteuspto-grants-2005_04