Triphenylphosphine → 6-Methoxy-2-(4-Methoxyphenyl)-3-(4-[2-Piperidin-1-ylcyclohexoxy]benzoyl)benzo[b]thiophene

HRID 181663Notes

Reaction equation

HRID 181663 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([s:8][c:9](-[c:20]3[cH:21][cH:22][c:23]([O:26][CH3:27])[cH:24][cH:25]3)[c:10]2[C:11]([c:12]2[cH:13][cH:14][c:15]([OH:18])[cH:16][cH:17]2)=[O:19])[cH:28]1.[N:29]1([CH:35]2[CH:36]([OH:41])[CH2:37][CH2:38][CH2:39][CH2:40]2)[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]1.[O:61]=[C:62]([O:63][CH2:64][CH3:65])[N:66]=[N:67][C:68]([O:69][CH2:70][CH3:71])=[O:72].[c:42]1([P:43]([c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[cH:56][cH:57][cH:58][cH:59][cH:60]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([s:8][c:9](-[c:20]3[cH:21][cH:22][c:23]([O:26][CH3:27])[cH:24][cH:25]3)[c:10]2[C:11]([c:12]2[cH:13][cH:14][c:15]([O:18][CH:36]3[CH:35]([N:29]4[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]4)[CH2:40][CH2:39][CH2:38][CH2:37]3)[cH:16][cH:17]2)=[O:19])[cH:28]1

Participants

5

Reactant 4

HCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 98651972-(4-Methoxyphenyl)-3-(4-Hydroxybenzoyl)-6-Methoxybenzo[b]thiopheneHCID 131196932-Piperidin-1-yl-cyclohexanol

Product 1

HCID 99156936-Methoxy-2-(4-Methoxyphenyl)-3-(4-[2-Piperidin-1-ylcyclohexoxy]benzoyl)benzo[b]thiophene

Sources & evidence

ORD record
ord-991ff8ee3b28425ca7e9b95d58045197
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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