Ethyl 2-chloroacetoacetate → HCID 22494322, compound

HRID 1816630Notes

Reaction equation

Cl[CH:2]([C:8]([CH3:10])=O)[C:3]([O:5]CC)=[O:4].[CH:11]1([C:16](=[S:18])[NH2:17])[CH2:15][CH2:14][CH2:13][CH2:12]1>>[CH:11]1([C:16]2[S:18][C:8]([CH3:10])=[C:2]([C:3]([OH:5])=[O:4])[N:17]=2)[CH2:15][CH2:14][CH2:13][CH2:12]1

Participants

Reactant 2

HCID 11858Ethyl 2-chloroacetoacetate

HCID 22141080Cyclopentanecarbothioamide

Product 1

HCID 22494322HCID 22494322, compound

Procedure

Ethyl 2-chloroacetoacetate and 1-cyclopentane carbothioamide were treated as the starting materials by the same method as in Production Example 203, to give 2-cyclopentyl-5-methyl-1,3-thiazole-4-carboxylic acid.

Sources & evidence

ORD record: ord-b988a006a8374a5994ca5e0a68d97973
Source dataset: uspto-grants-2005_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06884821B1

Reaction notes

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