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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816637Generated: October 26, 2026

2-Fluoro-4-(trifluoromethyl)benzyl alcohol → 3-[3-([2-Fluoro-4-(trifluoromethyl)benzyl]oxymethyl)-4-methoxyphenyl]-2-isopropoxypropanoic acid

https://huagongshe.com/reaction/1816637

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-4-(trifluoromethyl)benzyl alcoholHCID 2737561—
Reactant3-[3-(Bromomethyl)-4-methoxyphenyl]-2-isopropoxypropanoateHCID 22493893—
Product3-[3-([2-Fluoro-4-(trifluoromethyl)benzyl]oxymethyl)-4-methoxyphenyl]-2-isopropoxypropanoic acidHCID 22494179—

Reaction Steps

Using 2-fluoro-4-(trifluoromethyl)benzyl alcohol and 3-[3-(bromomethyl)-4-methoxyphenyl]-2-isopropoxypropanoate, 3-[3-([2-fluoro-4-(trifluoromethyl)benzyl]oxymethyl)-4-methoxyphenyl]-2-isopropoxypropanoic acid was obtained in the same method as in Example 247).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884821B1
Source datasetuspto-grants-2005_04
ORD IDord-e4b6d02b14aa4421a760805dbb5ee91d
Source noteuspto-grants-2005_04