1-Iodopropane → 2-Chloro-4-propoxybenzoic acid

HRID 1816651Notes

Reaction equation

[Cl:1][C:2]1[CH:11]=[C:10]([OH:12])[CH:9]=[CH:8][C:3]=1[C:4]([O:6]C)=[O:5].[CH2:13](I)[CH2:14][CH3:15]>>[Cl:1][C:2]1[CH:11]=[C:10]([O:12][CH2:13][CH2:14][CH3:15])[CH:9]=[CH:8][C:3]=1[C:4]([OH:6])=[O:5]

Participants

Reactant 2

HCID 336431-Iodopropane

HCID 134988302-Chloro-4-hydroxy-benzoic acid methyl ester

Product 1

HCID 224943262-Chloro-4-propoxybenzoic acid

Procedure

Using methyl 2-chloro-4-hydroxybenzoate and propyl iodide, 2-chloro-4-propoxybenzoic acid was obtained in the same manner as in Example 277b).

Sources & evidence

ORD record: ord-5826526930f94ac48448a13d0b4c9f00
Source dataset: uspto-grants-2005_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06884821B1

Reaction notes

Loading…