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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816669Generated: November 1, 2026

p-Bromochlorobenzene → 3,4'-Dichloro[1,1'-biphenyl]-4-carboxylic acid

https://huagongshe.com/reaction/1816669

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-BromochlorobenzeneHCID 7806—
ReactantMethyl 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoateHCID 22493932—
Product3,4'-Dichloro[1,1'-biphenyl]-4-carboxylic acidHCID 22493866—

Reaction Steps

Using methyl 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)benzoate and 4-bromochlorobenzene, 2-chloro-4-(4′-chlorophenyl)benzoic acid was obtained in the same method as in Production Example 292b).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884821B1
Source datasetuspto-grants-2005_04
ORD IDord-5c1d93c9cafb4abd8b75f28cb1e2d181
Source noteuspto-grants-2005_04