Methyl iodide → 1,1-Dimethyl-4-oxopiperidin-1-ium iodide

HRID 1816778Notes

Reaction equation

HRID 1816778 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][CH2:3]1.[I:9]C.[CH:11](OC(C)C)(C)C>ClCCl>[I-:9].[CH3:1][N+:2]1([CH3:11])[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][CH2:3]1

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 7914Diisopropyl EtherHCID 740491-Methyl-4-piperidone

Product 1

HCID 111494971,1-Dimethyl-4-oxopiperidin-1-ium iodide

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 1-methyl-4-piperidone (1.0 g) in dichloromethane (5 ml) was slowly added iodomethane (1 ml) at 0° C. and stirred for 30 minutes at ambient temperature. To the reaction mixture was added isopropyl ether (10 ml), and the resulting precipitate was collected by filtration to give 1,1-dimethyl-4-oxopiperidinium iodide (1.416 g).

Workup

  1. customat 0° C.
  2. filtrationthe resulting precipitate was collected by filtration

Sources & evidence

ORD record
ord-95c9d8f481364552aad5dab33211a869
Source dataset
uspto-grants-2005_04
Patent number
US06884868B1

Reaction notes

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