Hydroxylamine → HCID 86615833, compound

HRID 1816855Notes

Reaction equation

HRID 1816855 reaction equation
[OH:1][NH2:2].[C:3]1(=[O:9])[O:8][C:6](=[O:7])[CH2:5][CH2:4]1>C1C=CC=CC=1.N1C=CC=CC=1>[C:3]([OH:8])(=[O:9])[CH2:4][CH2:5][C:6]([OH:1])=[O:7].[NH2:2][OH:1]

Participants

5

Reactant 2

HCID 787HydroxylamineHCID 7922Succinic anhydride

Product 1

HCID 86615833HCID 86615833, compound

Reagents, catalysts & solvents 2

HCID 241BenzeneSolventHCID 1049PyridineSolvent

Procedure

This example that demonstrates how this method could be performed. Part 1: To a solution of 2 g hydroxy amine in 100 ml dry benzene and 100 ml pyridine, 9.4 g succinic anhydride is added and the reaction mixture stirred at room temperature for 2 h and refluxed for 2 h. The solvent is evaporated under vacuum and the residue is purified by flash chromatography using silica gel.

Workup

  1. temperaturerefluxed for 2 h
  2. customThe solvent is evaporated under vacuum
  3. customthe residue is purified by flash chromatography

Sources & evidence

ORD record
ord-cf7ae37b9589404c917f1cb762cf28c2
Source dataset
uspto-grants-2009_10
Patent number
US07597882B2

Reaction notes

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