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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816859Generated: November 2, 2026

Benzyl Bromide → 1-Bromo-4-phenylmethoxybenzene

https://huagongshe.com/reaction/1816859

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
Reactant4-BromophenolHCID 7808—
SolventDimethylformamideHCID 6228—
Product1-Bromo-4-phenylmethoxybenzeneHCID 138835—

Reaction Conditions

Temperature80 °C

Reaction Steps

To a solution composed of p-bromophenol (17.3 g, 0.1 mol) and dry DMF (100 mL), anhydride K2CO3 (8.28 g, 0.06 mmol) and benzyl bromide (25.6 g, 0.15 mmol) were added. The mixture was stirred at 80° C. under a nitrogen atmosphere for six hours. Then, the reaction mixture was charged into 500 mL of ice water.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07597980B2
Source datasetuspto-grants-2009_10
ORD IDord-5e11c941b17046ef94b03835ee80a6cd
Source noteuspto-grants-2009_10