Hydrochloric Acid → HCID 135540434, compound

Participants

Reaction Conditions

Reaction Steps

Acetic acid (40 ml) and concentrated hydrochloric acid (40 ml) were added to 7-(4-benzyloxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine (the compound obtained in Reference Example 2; 5.70 g), and the obtained mixture was stirred at 80° C. for 3 hours. The resultant product was concentrated under a reduced pressure, and the residue was then washed by suspension in acetone (200 ml) and then in a 50% ethanol solution (100 ml) to obtain the captioned compound (2.60 g).

Provenance & Evidence