HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57880551, compound → HCID 24904374, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57880551 | HCID 57880551 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 24904374 | HCID 24904374 | — |
Reaction Steps
tert-Butyl 4-[4-fluoro-3-(methoxycarbonyl)phenyl]piperidine-1-carboxylate (471 mg, 1.40 mmol) was dissolved in anhydrous 4N HCl in dioxane (5mL) and stirred at r.t. for 40 min. The white solid was filtered and washed with Et2O to afford methyl 2-fluoro-5-piperidin-4-ylbenzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598243B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-6a9bd24d76764080b34f4f2f40b5d57c |
| Source note | uspto-grants-2009_10 |