Trifluoroacetic acid → HCID 9855936, compound

HRID 1817028Notes

Reaction equation

HRID 1817028 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:9]2[C@H:16]3[C@H:11]([CH2:12][CH2:13][N:14](C(OC(C)(C)C)=O)[CH2:15]3)[CH2:10]2)[CH:6]=[N:7][CH:8]=1.FC(F)(F)C(O)=O>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:9]2[C@H:16]3[C@H:11]([CH2:12][CH2:13][NH:14][CH2:15]3)[CH2:10]2)[CH:6]=[N:7][CH:8]=1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 66757213HCID 66757213, compound

Product 1

HCID 9855936HCID 9855936, compoundYield 91.2%

Procedure

The product of Example 88A (0.540 g, 1.70 mmol) and trifluoroacetic acid were processed according to the procedure described in Example 64C to provide the title compound (0.340 g, 1.55 mmol, 91% yield).

Sources & evidence

ORD record
ord-1646ddafefc944e6bd0c7b08677409b9
Source dataset
uspto-grants-2009_10
Patent number
US07598236B2

Reaction notes

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