Methyl 4-bromobutyrate → HCID 86598625, compound

HRID 1817143Notes

Reaction equation

HRID 1817143 reaction equation
C[O:2][C:3](=[O:8])[CH2:4][CH2:5][CH2:6]Br.[CH3:9][O:10][C:11]1[CH:55]=[C:54]([O:56][CH3:57])[CH:53]=[C:52]([O:58][CH3:59])[C:12]=1/[CH:13]=[CH:14]/[CH:15]([S:25]([CH:28](/[CH:38]=[CH:39]/[C:40]1[C:45]([O:46][CH3:47])=[CH:44][C:43]([O:48][CH3:49])=[CH:42][C:41]=1[O:50][CH3:51])[C:29]1[CH:34]=[CH:33][C:32]([O:35][CH3:36])=[C:31]([NH2:37])[CH:30]=1)(=[O:27])=[O:26])[C:16]1[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[C:18]([NH2:24])[CH:17]=1>>[CH3:59][O:58][C:52]1[CH:53]=[C:54]([O:56][CH3:57])[CH:55]=[C:11]([O:10][CH3:9])[C:12]=1/[CH:13]=[CH:14]/[CH:15]([S:25]([CH:28](/[CH:38]=[CH:39]/[C:40]1[C:41]([O:50][CH3:51])=[CH:42][C:43]([O:48][CH3:49])=[CH:44][C:45]=1[O:46][CH3:47])[C:29]1[CH:34]=[CH:33][C:32]([O:35][CH3:36])=[C:31]([NH:37][CH2:6][CH2:5][CH2:4][C:3]([OH:8])=[O:2])[CH:30]=1)(=[O:27])=[O:26])[C:16]1[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[C:18]([NH:24][CH2:6][CH2:5][CH2:4][C:3]([OH:2])=[O:8])[CH:17]=1

Participants

3

Reactant 2

HCID 107604Methyl 4-bromobutyrateHCID 67401517HCID 67401517, compound

Product 1

HCID 86598625HCID 86598625, compound

Procedure

A solution of methyl-4-bromobutyrate (40 mmol) and (E)-2,4,6-trimethoxystyryl-3-amino-4-methoxybenzylsulfone (10 mmol) was reacted according to General Method B. The product obtained was purified by recrystallization from acetone. (m.p. 86-88° C.)

Workup

  1. customThe product obtained
  2. customwas purified by recrystallization from acetone

Sources & evidence

ORD record
ord-8b76740dcf4f4930942de081b49e7148
Source dataset
uspto-grants-2009_10
Patent number
US07598232B2

Reaction notes

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