HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Bromoacetophenone → 4-(4-Methyl-1-piperazinyl)acetophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Bromoacetophenone | HCID 7466 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Catalyst | Copper | HCID 23978 | — |
| Catalyst | Copper iodide | HCID 83717 | — |
| Product | 4-(4-Methyl-1-piperazinyl)acetophenone | HCID 33551 | 82% |
Reaction Steps
In a procedure identical to Example 53, 4-bromoacetophenone was reacted with N-methylpiperazine in the presence of potassium carbonate, copper and copper iodide to furnish the desired product in 82% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598272B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-800bb4628aab44fc9ea915a9342a89d3 |
| Source note | uspto-grants-2009_10 |