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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1817796Generated: October 29, 2026

1,3-Cyclohexanedione → 5-Oxo-2-thioxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile

https://huagongshe.com/reaction/1817796

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-CyclohexanedioneHCID 10434—
Reactant7,7-Dimethyl-5-oxo-2-thioxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrileHCID 1934680—
Product5-Oxo-2-thioxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrileHCID 184996752%

Reaction Steps

Prepared in 52% yield from cyclohexane-1,3-dione in analogy to the procedure described for 7,7-dimethyl-5-oxo-2-thioxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile synthesis.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07598384B2
Source datasetuspto-grants-2009_10
ORD IDord-f653c2b90143492fb7bc658c11944c46
Source noteuspto-grants-2009_10