HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 2-chloro-2,5a,6,7,8,9,9a,10-octahydro-1H-benzo[g]quinolin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 6,7,8,9,9a,10-hexahydrobenzo[g]quinoline-2,5(1H,5aH)-dione | HCID 57883270 | — |
| Product | 2-chloro-2,5a,6,7,8,9,9a,10-octahydro-1H-benzo[g]quinolin-5-one | HCID 69038159 | — |
Reaction Steps
In close analogy to (Shanazarov, A. K.; Kuzovkin, V. A.; Chistjakov, V. V.; Granik, V. G. Khim. Geterotsikl. Soedin. 1991, (1) 86-92) 6,7,8,9,9a,10-hexahydro-1H,5aH-benzo[g]quinoline-2,5-dione was treated with phosphoryl chloride (POCl3) to give after chromatographical separation the title compound as a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598384B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-a6763bb8d10b4c90a36717cb346ea407 |
| Source note | uspto-grants-2009_10 |