Isobutanol → HCID 11323896, compound

HRID 1817821Notes

Reaction equation

HRID 1817821 reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:8](=[O:12])[CH2:7][C:6]([CH3:14])(C)[CH2:5][C:4]=2[N:3]=1.[CH2:15]([OH:19])[CH:16]([CH3:18])[CH3:17]>>[CH2:15]([O:19][C:2]1[CH:11]=[CH:10][C:9]2[C:8](=[O:12])[CH2:7][CH:6]([C:14]3[CH:6]=[CH:5][CH:4]=[CH:9][CH:8]=3)[CH2:5][C:4]=2[N:3]=1)[CH:16]([CH3:18])[CH3:17]

Participants

3

Reactant 2

HCID 6560IsobutanolHCID 148125452-Chloro-7,7-dimethyl-7,8-dihydroquinolin-5(6H)-one

Product 1

HCID 11323896HCID 11323896, compoundYield 35%

Procedure

In analogy to the procedure described in Example 8, 2-chloro-7,7-dimethyl-7,8-dihydro-6H-quinolin-5-one was treated with iso-butyl alcohol to give the title compound in 35% yield.

Sources & evidence

ORD record
ord-3627f2ebfd4e492c91426bd0f3d7930b
Source dataset
uspto-grants-2009_10
Patent number
US07598384B2

Reaction notes

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