Hydrochloric Acid → HCID 86616217, compound

HRID 1817844Notes

Reaction equation

HRID 1817844 reaction equation
[CH:1]1([C:7]2[CH:8]=[CH:9][C:10]([O:34][CH3:35])=[C:11]([C:13]3[N:14]=[C:15]([NH:18][C:19]([CH:21]4[CH2:26][CH2:25][N:24](C(OC(C)(C)C)=O)[CH2:23][CH2:22]4)=[O:20])[S:16][CH:17]=3)[CH:12]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Cl>C(OCC)C>[CH:1]1([C:7]2[CH:8]=[CH:9][C:10]([O:34][CH3:35])=[C:11]([C:13]3[N:14]=[C:15]([NH:18][C:19]([CH:21]4[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]4)=[O:20])[S:16][CH:17]=3)[CH:12]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86616216HCID 86616216, compound

Product 1

HCID 86616217HCID 86616217, compoundYield 111.8%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of 1.13 g of the compound prepared in step 1.1 in 10 mL of a 4 M solution of HCl in ioxane is stirred for 30 minutes at room temperature. The medium is diluted with ethyl ether and then filtered. The solid thus obtained is rinsed with ether and then dried to give 1.01 g of a white solid.

Workup

  1. filtrationfiltered
  2. customThe solid thus obtained
  3. washis rinsed with ether
  4. customdried

Sources & evidence

ORD record
ord-064186bfed0440809591341344c39e0a
Source dataset
uspto-grants-2009_10
Patent number
US07598392B2

Reaction notes

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