Hydrochloric Acid → HCID 68871190, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Step F of Example 1 using 2-amino-1-(N-cyclopropylmethylamino)-4-(methylsulfonyl)benzene instead of 2-amino-1-(N-cyclopropylmethylamino)-4-(isopropylsulfonyl)benzene. Obtained 1-(cyclopropylmethyl)-2-(2,2-dimethylpropyl)-5-(methylsulfonyl)-1H-benzimidazole was dissolved in ethyl acetate and to the solution was added 4 N hydrogen chloride in ethyl acetate. Precipitate was collected by filtration to afford the title compound as a white solid.

Provenance & Evidence