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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1817857Generated: October 31, 2026

2-Cyclopropylacetyl chloride → 1,2-bis(Cyclopropylmethyl)-5-(isopropylsulfonyl)-1H-benzimidazole

https://huagongshe.com/reaction/1817857

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Cyclopropylacetyl chlorideHCID 14326268—
Reactant2-Amino-1-(N-cyclopropylmethylamino)-4-(isopropylsulfonyl)benzeneHCID 68869991—
Product1,2-bis(Cyclopropylmethyl)-5-(isopropylsulfonyl)-1H-benzimidazoleHCID 57883985—

Reaction Steps

The title compound was prepared according to the procedure described in Step C of Example 5 from cyclopropylacetyl chloride (Step A) and 2-amino-1-(N-cyclopropylmethylamino)-4-(isopropylsulfonyl)benzene (Step E of Example 1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07598393B2
Source datasetuspto-grants-2009_10
ORD IDord-2ee932ac5b2a456b89460443e5e4415c
Source noteuspto-grants-2009_10