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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1817868Generated: October 26, 2026

1-Chloro-4-(isopropylsulfonyl)-2-nitrobenzene → 4-({[4-(Isopropylsulfonyl)-2-nitrophenyl]amino}methyl)tetrahydro-2H-pyran-4-ol

https://huagongshe.com/reaction/1817868

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-4-(isopropylsulfonyl)-2-nitrobenzeneHCID 23559202—
Reactant4-(Aminomethyl)oxan-4-ol--hydrogen chloride (1/1)HCID 57345814—
SolventTriethylamineHCID 8471—
Product4-({[4-(Isopropylsulfonyl)-2-nitrophenyl]amino}methyl)tetrahydro-2H-pyran-4-olHCID 68870723—

Reaction Steps

The title compound was prepared according to the procedure described in Step A of Example 5 from 1-chloro-4-(isopropylsulfonyl)-2-nitrobenzene (Step C of Example 1), 4-(aminomethyl)tetrahydro-2H-pyran-4-ol hydrochloride (Step A of Example 19) and triethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07598393B2
Source datasetuspto-grants-2009_10
ORD IDord-094f52bf22d54b69a84cf71130ba3843
Source noteuspto-grants-2009_10