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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1817876Generated: October 29, 2026

4-Aminomethyltetrahydropyran → 5-(Isopropylsulfonyl)-3-nitro-N-(tetrahydro-2H-pyran-4-ylmethyl)pyridin-2-amine

https://huagongshe.com/reaction/1817876

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminomethyltetrahydropyranHCID 2773210—
Reactant2-Chloro-5-(isopropylsulfonyl)-3-nitropyridineHCID 86241979—
Product5-(Isopropylsulfonyl)-3-nitro-N-(tetrahydro-2H-pyran-4-ylmethyl)pyridin-2-amineHCID 68871366—

Reaction Steps

The title compound was prepared according to the procedure described in Step A of Example 5 from 2-chloro-5-(isopropylsulfonyl)-3-nitropyridine (Step D of Example 22) and 4-aminomethyltetrahydropyran (Apollo Scientific Ltd.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07598393B2
Source datasetuspto-grants-2009_10
ORD IDord-1d07601dccef4141a9e52ee35acbd709
Source noteuspto-grants-2009_10