Hydrochloric Acid → HCID 68869381, compound

Participants

Reaction Steps

To a solution of 2-tert-butyl-5-(ethylsulfonyl)-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazole (Step A, 113 mg, 0.31 mmol) in ethyl acetate (3 mL) was added 4 N hydrogen chloride in ethyl acetate (1 mL). The mixture was concentrated and the residue was recrystalized from ethyl acetate and methanol to afford the title compound (92.5 mg, 0.23 mmol, 74%) as a white solid.

Provenance & Evidence