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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1817905Generated: October 27, 2026

1-Fluoro-4-methanesulfonyl-2-nitrobenzene → 4-(Methylsulfonyl)-2-nitro-N-(tetrahydro-2H-Pyran-4-ylmethyl)aniline

https://huagongshe.com/reaction/1817905

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Fluoro-4-methanesulfonyl-2-nitrobenzeneHCID 313137—
Reactant4-AminomethyltetrahydropyranHCID 2773210—
Product4-(Methylsulfonyl)-2-nitro-N-(tetrahydro-2H-Pyran-4-ylmethyl)anilineHCID 62351026—

Reaction Steps

The title compound was prepared according to the procedure described in Step A of Example 5 from 1-fluoro-4-(methylsulfonyl)-2-nitrobenzene (Acros Organics Ltd.) and 4-aminomethyltetrahydropyran (Apollo Scientific Ltd.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07598393B2
Source datasetuspto-grants-2009_10
ORD IDord-9760c4ecee1a4b9abc7191a16c5cf884
Source noteuspto-grants-2009_10